Amorfrutins are potent antidiabetic dietary natural products. pdfWeidner C, de Groot JC, Prasad A, Freiwald A, Quedenau C, Kliem M, Witzke A, Kodelja V, Han CT, Giegold S, Baumann M, Klebl B, Siems K, Müller-Kuhrt L, Schürmann A, Schüler R, Pfeiffer AF, Schroeder FC, Büssow K, Sauer S.
The phytochemical glaucarubinone promotes mitochondrial metabolism, reduces body fat, and extends lifespan of Caenorhabditis elegans. webZarse, K.; Bossecker, A.; Mueller-Kuhrt, L.; Siems, K.; Hernandez, M. A.; Berendsohn, W. G.; Birringer, M.; Ristow, M. Horm. Metab. Res. (2011), 43(4), 241-243
Revisiting old drugs as novel agents for retinoblastoma: in vitro and in vivo antitumor activity of cardenolides. webAntczak Christophe; Kloepping Carolyn; Radu Constantin; Genski Thorsten; Muller-Kuhrt Lutz; Siems Karsten; de Stanchina Elisa; Abramson David H; Djaballah Hakim
Structure-Based Pharmacophore Screning for Natural-Product-Derived PPARγ Agonists webYusuf Tanrikulu, Oliver Rau, Oliver Schwarz, Ewgenij Proschak, Karsten Siems, Lutz Müller-Kuhrt, Manfred Schubert-Zsilavecz, and Gisbert Schneider
A Cell-based High-throughput Assay System Reveals Modulation of Oxidative and Nonoxidative Glucose Metabolism due to Commonly Used Organic Solvents webS. Zimmermann, K. Zarse, T. J. Schulz, K. Siems, L. Müller-Kuhrt, M. Birringer, M. Ristow
Burning the Hay to Find the Needle-Data Mining Strategies in Natural Product Dereplication webD. Wolf and K. Siems
Identification of Natural-Product-Derived Inhibitors of 5-Lipoxygenase Activity by Ligand-Based Virtual Screening webLutz Franke, Oliver Schwarz, Lutz Müller-Kuhrt, Christina Hoernig, Lutz Fischer, Sven George, Yusuf Tanrikulu, Petra Schneider, Oliver Werz, Dieter Steinhilber, and Gisbert Schneider
Natural Products in Parallel Chemistry – Novel 5-Lipoxygenase Inhibitors from BIOS-Based Libraries Starting from α-Santonin webOliver Schwarz, Sven Jakupovic, Horst-Dieter Ambrosi, Lars Ole Haustedt, Christian Mang, and Lutz Müller-Kuhrt
Successful, but often unconventional: the continued and long-term contribution of natural products to healthcare webLutz Müller-Kuhrt
Discovery of protein phosphatase inhibitors classes by biology-oriented synthesis webAndrea Nören-Müller, Ivan Reis-Corrêa, Jr., Heino Prinz, Claudia Rosenbaum, Krishna Saxena, Harald J. Schwalbe, Dietmar Vestweber, Guiseppe Cagna, Stefan Schunk, Oliver Schwarz, Hajo Schiewe and Herbert Waldmann
Rational approaches to natural-product-based drug design Lars Ole Haustedt, Christian Mang, Karsten Siems and Hajo Schiewe
Natural Products in Combinatorial Chemistry: An Andrographolide-Based Library webChristian Mang, Sven Jakupovic, Stefan Schunk, Horst-Dieter Ambrosi, Oliver Schwarz, and Jasmin Jakupovic
